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Annual SBN Meeting Poster Awards!

Congratulations to the Best Postdoctoral and Best Graduate Student Poster winners!
In Memoriam: Shelton Hendricks

Shelton Hendricks has died at age 75 after a long illness. Dr. Hendricks was one of the founding members of the SBN’s predecessor, the Conference on Reproductive Behavior, and he hosted the annual meeting once in Omaha.

Welcome from the President

SBN President Cheryl Sisk.

GREETINGS TO ALL SBN MEMBERS!
I am delighted and honored to be your new President. SBN is a wonderful organization that provides significant benefits to its members. I look forward to helping the society meet your interests and needs in science and professional development, and I encourage you to share your ideas about how SBN can best serve you.

—Elizabeth Adkins-Regan

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The Society for Behavioral Neuroendocrinology offers four levels of eligibility for prospective members: Regular, Emeritus, Student, or Associate Memberships.

To see which membership class you qualify for, please review the membership eligibility requirements.

For additional information on SBN and the rules of membership, please see the SBN Bylaws.

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Elected Officers

PRESIDENT (2015-2017) Elizabeth Adkins-Regan

PRESIDENT-ELECT (2015-20175) Rae Silver

PAST PRESIDENT (2015-2017) Cheryl Sisk

SECRETARY (2015-2017) Colin John Saldanha

TREASURER (2013-2016) Nancy Forger

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Hormones and Behavior

Tuesday, September 27, 2016
Publication date: November 2016
Source:Hormones and Behavior, Volume 86

Author(s): Raymundo Domínguez-Ordóñez, Marcos García-Juárez, Francisco J. Lima-Hernández, Porfirio Gómora-Arrati, Jeffrey D. Blaustein, Anne M. Etgen, Oscar González-Flores

The present study was designed to assess the participation of estrogen receptors alpha (ERα) and beta (ERβ) in the short-term facilitation of lordosis behavior in ovariectomized (ovx), estradiol (E2) primed rats. In experiment 1, dose response curves for PPT and DPN (ERα and ERβ agonists, respectively) facilitation of lordosis behavior (lordosis quotient and lordosis score) were established by infusing these agonists into the right lateral ventricle (icv) in female rats injected 40h previously with 5μg of E2 benzoate. PPT doses of 0.08 and 0.4ng produced high lordosis quotients starting at 30min and continuing at 120 and 240min post-injection. DPN induced high levels of lordosis behavior at all times tested. However, the intensity of lordosis induced by both agonists was weak. In experiment 2, we tested the involvement of each ER in facilitation of lordosis by icv infusion of MPP (ERα-selective antagonist) or PHTPP (ERβ-selective antagonist) prior to infusion of 2ng of free E2. Icv infusion of either MPP or PHTPP 30min before free E2 significantly depressed E2 facilitation of lordosis. The results suggest that both forms of ER are involved in the short-latency facilitation of lordosis behavior in E2-primed rats.

Tuesday, September 27, 2016
Publication date: November 2016
Source:Hormones and Behavior, Volume 86

Author(s): Nina Callens, Maaike Van Kuyk, Jet H. van Kuppenveld, Stenvert L.S. Drop, Peggy T. Cohen-Kettenis, Arianne B. Dessens

The magnitude of sex differences in human brain and behavior and the respective contributions of biology versus socialization remain a topic of ongoing study in science. The preponderance of evidence attests to the notion that sexual differentiation processes are at least partially hormonally mediated, with high levels of prenatal androgens facilitating male-typed and inhibiting female-typed behaviors. In individuals with Disorders/Differences of Sex Development (DSD), hormonal profiles or sensitivities have been altered due to genetic influences, presumably affecting gender(ed) activity interests as well as gender identity development in a minority of the affected population. While continued postnatal androgen exposure in a number of DSD syndromes has been associated with higher rates of gender dysphoria and gender change, the role of a number of mediating and moderating factors, such as initial gender assignment, syndrome severity and clinical management remains largely unclear. Limited investigations of the associations between these identified influences and gendered development outcomes impede optimization of clinical care. Participants with DSD (n=123), recruited in the context of a Dutch multi-center follow-up audit, were divided in subgroups reflecting prenatal androgen exposure, genital appearance at birth and gender of rearing. Recalled childhood play and playmate preferences, gender identity and sexual orientation were measured with questionnaires and semi-structured interviews. Data were compared to those of control male (n=46) and female participants (n=79). The findings support that (a) prenatal androgen exposure has large effects on (gendered) activity interests, but to a much lesser extent on sexual orientation and that (b) initial gender of rearing remains a better predictor of gender identity contentedness than prenatal androgen exposure, beyond syndrome severity and medical treatment influences. Nonetheless, 3.3% of individuals with DSD in our sample self-reported gender dysphoria from an early age and changed gender, which further underlines the need for thorough long- term follow-up and specific clinical support.

Tuesday, September 27, 2016
Publication date: November 2016
Source:Hormones and Behavior, Volume 86

Author(s): Joseph P. Huston, Mara Komorowski, Maria A. de Souza Silva, Valéria Lamounier-Zepter, Susanne Nikolaus, Claudia Mattern, Christian P. Müller, Bianca Topic

Withdrawal and avoidance behavior are common symptoms of depression and can appear as a consequence of absence of reward, i.e. extinction-induced depression (EID). This is particularly relevant for the aged organism subjected to pronounced loss of former rewards. Avoidance of the former site of reward and increased withdrawal into a distant compartment accompany extinction of food-rewarded behavior in rodent models. During extinction, behavioral markers for re-learning dissociate from indicators of extinction-induced depression. Here we examined the effect of a chronic treatment with corticosterone (CORT), a well-known inducer of depression-related behavior, on EID in adult and aged rats. Adult (3–4months) and aged (18months) male rats were treated with CORT via drinking water for 3weeks prior to extinction of a cued food-reward task. CORT treatment increased the distance from the site of reward and decreased goal tracking behavior during extinction, especially in the aged rats. Plasma hormone levels measured before and after restraint stress showed a decline in basal ACTH- and CORT-levels after chronic CORT treatment in aged animals. The treatment significantly impaired the HPA-axis activation after acute stress in both, adult and aged animals, alike. Altogether, these findings show an enhancement of EID after chronic CORT treatment in the aged organism, which may be mediated by an impaired HPA-axis sensitivity. These findings may have special relevance for the investigation of human geriatric depression.

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